What you need to do is provide information about both the original source and the source in which it was reprinted. If the column of sample is over 3 mm, discard the melting point tube and start again. Our recrystalized aspirin product had a melting point range of 110. Aspirin is an irreversible inhibitor that inhibits the synthesis of. This paper is an example of apa format dallas m stout university of the rockies abstract the purpose of this paper is to provide you with written instructions on some of the basic guidelines with the new apa format american psychological association, 2009. It also covers the treatment of numbers, statistical and mathematical data, tables and figures. Also, your melting point range may be greater than 2 degrees. The recrystallization and dissolution of acetylsalicylic acid ubc. Presents the history of the chemistry and preparation of aspirin.
Antagonistic activity mediated through d2 dopamine receptors in the. Fecl 3 color test for phenols another test on the purity of the final product is the very sensitive test for phenols given by fecl3. Haloperidol competitively blocks postsynaptic dopamine d2 receptors in the mesolimbic system of the brain, thereby eliminating dopamine neurotransmission and leading to antidelusionary and antihallucinagenic effects. Making aspirin chemistry bibliographies cite this for me. Aspirin is effective in reducing fever, inflammation, and swelling and thus has been used for treatment of rheumatoid arthritis, rheumatic fever, and mild infection. Aqueous solutions of acetylsalicylic acid are most stable at ph 2. The acs style guide is generally used for academic writing in chemistry. You are provided with a small sample of pure aspirin in a melting point tube. Apa format 1 inch margins, in text citations, times new roman font 12, page numbers, running head, etc. Acetylsalicylic acid, european pharmacopoeia ep reference standard acetylsalicylic acid.
What is the melting point of aspirin using hard copy. In general will the melting point of an aspirin tablet be higher or lower than that of pure lab made aspirin powder. Aspirin is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antiinflammatory compound that inhibits cox1. The r f values have little significance in determining purity in the aspirin product because all the samples have relatively close results thus not proving the purity content in the aspirin product. The first part of the experiment aims to synthesize aspirin from the reaction of salicylic acid with acetic anhydride with the aid of phosphoric acid as a catalyst. Due to its wide range, and lower value than that of the theoretical melting point of 6c, it was assessed that the prepared aspirin was impure.
According to the melting point values, the aspirin product does not resemble pure aspirin because the melting point range was off by a little and was a bit too high. At last,acetylsalicylic acid50782 safety, risk, hazard and msds, cas,cas number,use,cas. The melting point range of the created product 1262 degrees celsius was lower than that for pure aspirin 1205degrees celsius. Acetylsalicylic acid is slightly soluble in water, with a limit of solubility reported as approximately 3 mgml at 25 deg c. You may find information in reference books, in libraries, in pharmacies and by. Reference page strict apa style expected appendices include copies of survey instrument, interview questions, etc. Miscellaneous the melting point of acetylsalicylic acid published by permission of the chairman of the committee of revision, u.
Create your citations, reference lists and bibliographies automatically using the apa, mla, chicago, or harvard referencing styles. Top, uvvisible spectrum, references data from nist standard reference database 69. Furthermore, the other objectives were to enable students to conduct the synthesis of aspirin, reinforce skills or recrystallisation and the technique of melting point determination. If impurities are present in your crude sample, the melting point range for your product will be lower than the range of pure aspirin. I need help on writing up the analysis and evaluating the accuracy of the methods used to estimate the purity. The theory melting point is 140 isc and the experiment melting point range is 4. This bibliography was generated on cite this for me on friday, july 1, 2016. The melting point range of pure aspirin is 8140 c and the melting point range of the salicylic acid starting material is 158161 c.
It is also soluble in ethanol at 50 mgml and will dissolve in solutions of alkali hydroxides and carbonates with decomposition. Generate an infrared spectrum of your aspirin sample your instructor will demonstrate how to use the ft. Results page 7 about sample apa synthesis free essays. Hello,so there was an experiment that was taken place,which was melting point of aspirin,test the purity. C, which is slightly lower than the literature range for aspirin of 46. Aspirin synthesis chemistry bibliographies cite this. What is the melting point of aspirin using hard copy material text book and not the internet. A particularly good source for determining the correct way to cite material found on khan academy for apa. The first part of the experiment aims to synthesize aspirin from the reaction of salicylic acid with acetic anhydride with the aid of.
Aspirin synthesis lab report by eddie zhang on prezi. Preparation of aspirin and determination of the melting point. We offer publicly available, official documentary standards for pharmaceutical ingredients in the usp nf that link directly with a primary reference standard. Aspirin synthesis chemistry bibliographies in harvard style. Acetaminophen is a medicine used to relieve pain and reduce fever purpose. The objective was to convert a specific amount of salicylic acid into the same amount of aspirin that was high in purity. Recrystallization and melting point experimental procedure. Example if the site was accessed on the 24th of january 2017. Synthesis of aspirin and determination of melting point a. Ama apa 6th edition apa 7th edition chicago 17th edition, authordate harvard ieee iso 690 mhra 3rd edition mla 8th edition oscola turabian 9th edition vancouver cite join us.
The r f values have little significance in determining purity in the aspirin product because all the samples have relatively close results thus not. Page headers identify each page with the page number placed in the header at the right margin. Determine the melting point of your aspirin sample your instructor will demonstrate how to use the melttemp apparatus. Results page 4 about sample apa synthesis free essays. Apr 17, 2009 in general will the melting point of an aspirin tablet be higher or lower than that of pure lab made aspirin powder. Aspirin melting point essay medicine and health articles. The search on this page works by searching the content of each page individually, much like any web search. In the next activity you measure the melting point of your sample before and. Since the melting point of the recrystallized aspirin falls within the temperature range of 129. Determination of purity phenols form a colored complex with the ferric ion. According to the melting point values the aspirin product. In apa format, only the first letter of the title should be capitalized, along with the first letters of any proper nouns. When we tested the melting point, the range was 106118.
The synthesis of aspirin is classified as an esterification reaction. A pure sample of a substance will melt at a sharply defined temperature, an impure sample will show a larger range. In addition to providing guidance on grammar, the mechanics of writing, and apa style, this manual offers an authoritative reference and citation system. Since the melting point of pure aspirin is 8140, this means that our aspirin was. The documented value for the melting point of pure aspirin is 5 degrees celsius.
A sample of the salicylic acid was weighed and then a measured amount of acetic anhydride and a minimal amount of sulphuric acid was also added. Mar 01, 2007 the problem with getting a value for the melting point of an organic substance is the purity of the material. Nist chemistry webbook the national institute of standards and technology nist uses its best efforts to deliver a high quality copy of the database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. In lab today, we measured the actual yield and melting point of aspirin that we had made in lab last week. Aspirin, also known as acetylsalicylic acid asa, is a medication used to reduce pain, fever. The synthesis of aspirin, during the first step of the procedure, is classified as an esterification procedure. Haloperidol is a highly lipophilic compound and is extensively metabolized in humans, which may cause a large interindividual variability in its pharmacokinetics. The temperature is set to 100 isc and then gradually heated up to determine the melting point. Aspirin and measure its boiling point free essay example. When you are citing sources for a term paper, an excerpt of a work reprinted in another can be one of the trickiest types of sources to correctly format. Record the temperature where the melting point is first observed and when it becomes a liquid completely. Preparation and recrystallisation of aspirin contents page synopsis iii 1 introduction 1 1. Includes eight activities that can be used in a variety of teaching and learning situations.
A32346 studies have found a wide variance in pharmacokinetic values for orally administered haloperidol with 1. The melting point for aspirin was obtained to be 109 4 degrees celsius very from chem 3361 lab at kennesaw state university. Acetaminophen is used to relieve many kinds of minor aches and pains headaches, muscle aches, backaches, toothaches, menstrual cramps, arthritis, and the aches and pains that often accompany colds description. Haynes 20 preparing aspirin by reacting salicylic acid and acetic anhydride, and recording its melting point was the aim of this experiment. Chemistry aspirin lab question wyzant ask an expert. Describe briefly how you would determine an accurate value for the melting point of this aspirin. This is not an example of the work produced by our essay writing service. Synthesis of aspirin lab chem 165 linkedin slideshare. The narrow range of melting seems to indicate that the sample is pure, but the slightly depressed melting point doesnt support that. Pittsburgh pa section on practical pharmacy and dispensing, a. The melting point f purified aspirin varies between 5 c, temperature was noticed at the aspirin begins to melt and the sample has completely melted.
Usp reference standards are rigorously tested and evaluated by multiple independent commercial, regulatory, and academic laboratories to confirm accuracy and reproducibility. Aspirin, an acetyl derivative of salicylic acid, is a white, crystalline, weakly acidic substance, with a melting point of 6 c 277 f, and a boiling point of 140 c 284 f. Apa format 1 inch margins, intext citations, times new roman font 12, page numbers, running head, etc. This falls in the range of the pure aspirin, but not in the range of the synthesized product.
If you do not have at least 1 mm of sample, scoop another small portion and repeat. The experimental melting point range of aspirin was determined to be 122 2c. Firstly the tip of a capillary tube was put over a flame,it was important to make sure the capillary tube didnt start to bend and melt. If phenol is present in a sample, the resulting color means the product is impure. Acetaminophen is used to relieve many kinds of minor aches and pains headaches, muscle aches, backaches, toothaches, menstrual cramps, arthritis, and the aches and pains that often accompany colds.
Aspirin, british pharmacopoeia bp reference standard f21910068 z234893989. This guide provides a basic introduction to the acs citation style. Preparation and recrystallisation of aspirin 1796 words 8 pages. Below are basic explanations and examples for the most common types of citations used by students.
List the editor of the book in which the excerpt was reprinted. Synthesis and recrystallization of aspirin lab report. After recrystallizing aspirin and drying the crystals 2 days, i ran a melting point on the sample and obtained a range of 2. Apa format and style checklist general guidelines font style must be times new roman, arial, or courier new. Use a running head at the left margin of the header if your instructor requires it or. Mar 17, 2014 what is the melting point of aspirin using hard copy material text book and not the internet. The melting point of pure salicylic acid is 150 c, the melting point of pure aspirin is 5 c. Mar 09, 2020 in addition to providing guidance on grammar, the mechanics of writing, and apa style, this manual offers an authoritative reference and citation system. Recrystallization of the aspirin would remove unreacted salicylic acid and narrow the melting point range. How to do an excerpt in apa format pen and the pad. Batches of highly purified chemicals, intended for use as reference substances in the calibration of apparatus for meltingpoint determinations, have been subjected to a collaborative assay by 15 laboratories in countries. The crc handbook of chemistry and physics hbcp contains over 700 tables in over 450 documents which may be divided into several pages, all categorised into 17 major subject areas. Hence, the depression of the melting point of individual crystals is related to the increased. Jan 07, 20 hello,so there was an experiment that was taken place,which was melting point of aspirin,test the purity.
Compare the melting point you recorded to the melting point in the literature. Aspirin, derivative of salicylic acid that is a mild nonnarcotic analgesic useful in the relief of headache and muscle and joint aches. May 20, 2010 after recrystallizing aspirin and drying the crystals 2 days, i ran a melting point on the sample and obtained a range of 2. The melting point for aspirin was obtained to be 109 4. Insert the packed melting point tubes into a melting point apparatus. It is based on the 3rd edition of the acs style guide published by the american chemical society in 2006. Haloperidol is a phenylbutylpiperadine derivative with antipsychotic, neuroleptic, and antiemetic activities. Abstract aspirin is the common name for the compound acetylsalicylic acid, widely used as a fever reducer and as a pain killer. Aspirin is follows aspirin through its birth ancient sumer andor egypt using willow bark as medicinal treatment, childhood purification, chemical synthesis, adolescence the race for monopoly and profit, adulthood most popular drug on the planet, midlife crisis advent of new drugs such as tylenol and ibuprofen, and its sudden discovery that there is life after middleage use as. In addition, this paper is written in apa format to provide you with a visual image of how many. Simply put, esterification is a reaction between a.
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